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Inhibition of the Promotion Stage of Carcinogenesis by Decoctions and Expressed Juices from Philippine Medicinal Plants

The Bulletin of Philippine Biochemical Society
​Volume 11 & 12, Issue 1, 1992-1993, Pages 1-3
                                                
Authors
Eleanor Serrame and Clara Y. Lim-Sylianco

Institute of Chemistry, University of the Philippines - Diliman, Quezon City
​
Abstract                                                                                 
            When dimethylbenzanthracene was used as the initiator and croton oil as the promoter, 67% of the experimental micce developed skin tumors, 50% had liver tumors, 33% had colon tumors. These were observed after 20 weeks.
        Complete inhibition of formation of all types of tumors was exhibited by decoction from mango bark and expressed juices from leaves of guava, sulasi, kalatsutsi, yerba buena, pandan, kinchay, sabila, damong Maria, mayana and flowers of santan pula and santan dilaw.
        Partial inhibition of tumor formation was exhibited by expressed juice from garlic bulbs, leaves of alagaw, flowers from gumamela and decoction from kogon roots and leaves of romero. Expressed juice from onion bulbs inhibited the development of liver tumors but not skin tumors.
          It is possible that the test medicinal plants contain constituents that can inhibit the promotion stage of carcinogenesis.

Keywords: promotion, carcinogenesis, decoctions, medicinal plants.
             
To cite this article
E. Serrame and C.Y. Lim-Sylianco​, Inhibition of the Promotion Stage of Carcinogenesis by Decoctions and Expressed Juices from Philippine Medicinal Plants, The Bulletin of Philippine Biochemical Society, Vol. 11 & 12, No. 1, 1992-1993, pp.  1-3. 
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