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Antimutagenic Effects of Some Anticancer Agent

The Bulletin of Philippine Biochemical Society
​Volume 4, Issue 1 & 2, 1981, Pages 1-7
                                      
Authors
C.Y. Lim-Sylianco and F. Blanco 

Abstract
         Amygdalin, cyclophosphamide, and decoction of leaves of Catharanthus roseus (Linn.) Don. Were studied as regards to their antimutagenic effects, using the micronucleus technique. The test mutagens that were employed were dipyrone, metronidazole, mitomycin C and safrole.
             Amygdalin, cyclophosphamide, and decoction from leaves of Catharanthus roseus (Linn.) Don. Reduced the number of micronucleated polychromatic erythrocytes caused by the test mutagens. Highest antimutagenic effect was observed with decoction from leaves of Catharanthus roseus (Linn.) Don. Weakest effect was given by cyclophosphamide. An intermediate effect was shown by amygdalin.

To cite this article
C.Y. Lim-Sylianco and F. Blanco​, Antimutagenic Effects of Some Anticancer Agent, The Bulletin of Philippine Biochemical Society, Vol. 4, No. 1 & 2, 1981, pp. 1-7.     
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