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Characterization of the Mutagenic Component of Siling Labuyo

The Bulletin of Philippine Biochemical Society
​Volume 7, Issue 2, 1987, Pages 57-59
                                                
Authors
Herman Yee and Clara Y. Lim-Sylianco

CY Lim-Sylianco is a professor at the Institute of Chemistry, UP Diliman and an author of several books in Organic Chemistry and Biochemistry; H Yee is a research assistant from the same institute 

Abstract                                                      
                The ethyl acetate fraction of siling labuyo was found to be mutagenic and clastogenic. Thin layer chromatography on silica gel plates using chloroform and absolute ethanol (9:1) gave five spots. Only spot no. 5 was shown to be genotoxic as determined by the micronucleus test. The ultraviolet absorption spectrum, proton NMR spectrum, low resolution mass spectrum and HPLC data showed that spot no. 5 was not capsaicin. The mutagen in siling labuyo is not capsaicin, contrary to the claim in the literature. Further studies are necessary to determine the exact structure of spot no. 5.

To cite this article
H. Yee and C.Y. Lim-Sylianco​, Characterization of the Mutagenic Component of Siling Labuyo, The Bulletin of Philippine Biochemical Society, Vol. 7, No. 2, 1987, pp. 57-59. 
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