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Mutagenicity and Clastogenicity Potential of Five Philippine Medicinal Plants​

The Bulletin of Philippine Biochemical Society
​Volume 8, Issue 1, 1988-1989, Pages 17-21
                                                
Authors
C.Y. Lim-Sylianco, B. Basilio, L.C.V. Mendoza, D. Ang, M.C. Villena and S. Del Rosario

Dept. of Chemistry, College of Science, University of he Philippines - Diliman, Quezon City

Abstract                                                                   
          Expressions from rhizomes of Acorus calamus Linn., decoctions from leaves of Cassia tora Linn., seeds of Glycine max (Linn.) Merr., tubers of Kaempferia galangal Linn. And roots of Vetiveria zizanioides Stapf.were studied for mutagenicity and clastogenicity potential using Rec assay, Ames test, host-mediated assay and micronucleus test.
    The plant test systems did not possess direct DNA damaging capacity. These were not mutagenic before and after metabolic activation. No chromosome breaking effects were observed.

To cite this article
C.Y. Lim-Sylianco, B. Basilio, L.C.V. Mendoza, D. Ang, M.C. Villena and S. Del Rosario​, Mutagenicity and Clastogenicity Potential of Five Philippine Medicinal Plants​, The Bulletin of Philippine Biochemical Society, Vol. 8, No. 1, 1988-1989, pp. 17-21. 
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