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1978, volume 1
  • June 1978, Vol. 1, Issue 1
  • December 1978, Vol. 1, Issue 2​
1979, volume 2​
  • June 1979, Vol. 2, Issue 1
1980, volume 3
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  • June 1987, Vol. 7, Issue 1
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  • Vol. 9, Issue 1
1992-1993, VOLUME 11 & 12
  • Vol. 11 & 12, Issue 1​

Mutangenic and Clastogenic Effects of Chloroform                                   ​


The Bulletin of Philippine Biochemical Society
​Volume 1, Issue 2, 1978, Pages 17-23

Authors
Jovenal San Agustin and Clara Y. Lim-Sylianco*
         
*University of the Philippines - Diliman, Quezon City

Abstract
            Chloroform was shown to exhibit DNA damaging capacity. However, its DNA damaging capacity is not a consequence of its direct reactivity with DNA. Directly, it did not effect base pair and frameshift mutations. But chloroform is metabolized to a frameshift mutagen in the male mouse. Thus, chloroform is a pro-mutagen, although it is not a direct mutagen. It is not only a pro-mutagen but also a clastogen (chromosome breaking). Its clastogenicity and mutagenicity, however, is reduced in the presence of vitamin E.
​                                                       
To cite this article
J. San Agustin and C.Y. Lim-Sylianco​, 
Mutangenic and Clastogenic Effects of Chloroform, The Bulletin of Philippine Biochemical Society, Vol. 1, No. 2, 1978, pp. 17-23.      
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 Abstract

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  • Home
  • About
    • Constitution and By Laws
    • Board of Directors
    • Membership
    • Awards and Grants >
      • Awardees
      • Young Scientists' Forum
    • PSBMB Chapters >
      • North Luzon Chapter
      • Central Luzon Chapter
      • South Luzon Chapter
  • Conventions
    • 47th Annual Convention
    • 46th Annual Convention
    • 45th Annual Convention
  • RevUp and REdUp
    • 1st REdUp
    • 18th Review and Updates
  • News
  • Newsletter
  • PJBMB