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The Philippine Biochemical Society was founded in August 1973 by National Scientist Clara Lim-Sylianco, and together with other biochemists, the society centered on the development of biochemistry in the country. The society has aimed to improve knowledge in the field through research and education, and collaborations with fellow biochemists here and abroad which can help improve the socio-economic and health conditions of the country. 

The society has launched the first issue of its journal, The Bulletin of the Philippine Biochemical Society in June 1978. The Editorial Board was led by Dr. Relicardo M. Coloso as Editor-in-Chief, followed by its Assistant Editors Lourdes Brion, Gertrudes Buenaflor, Marilou Gagalac, Ramon Luber, Nemesio Montaño, Cynthia Pablo, Imelda Panizares and Enrico G. Camara. 

The journal release issues every June and December of the year and from June 1978 until 1993, the Bulletin has release a total of twelve volumes with twelve issues. PSBMB decided to re-launch the journal under its new name, The Philippine Journal of Biochemistry and Molecular Biology (PJBMB) which will start accepting submissions as early as January 2019, just in time to release its first issue  on June 2019.

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